SCHEMBL29490372

SCHEMBL29490372

COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cc3ccccn3)cc(OC)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 20/20 1.00
KAT7 O95251 19/20 1.00
KAT6B Q8WYB5 11/20 1.00
KAT5 Q92993 8/20 0.68
KAT8 Q9H7Z6 8/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22802451 1.00 KAT6A (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL25562559 0.94 KAT6A (0.88) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL30360845 0.94 KAT6A (0.88) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22817462 0.89 KAT6A (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL32681095 0.89 KAT6A (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22802517 0.89 KAT7 (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22828716 0.86 KAT7 (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL32681098 0.86 KAT7 (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22817461 0.86 KAT7 (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL32681094 0.85 KAT7 (0.75) KAT6AKAT7KAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114364672-B Benzisoxazole sulfonamide derivatives 辉瑞大药厂 2024-09-06 CN disclosed
EP-3986890-A1 BENZISOXAZOLE SULFONAMIDE DERIVATIVES Pfizer Inc. (US) 2022-04-27 EP disclosed
CN-114364672-A Benzisoxazole sulfonamide derivatives 辉瑞大药厂 2022-04-15 CN disclosed