SCHEMBL29490381

SCHEMBL29490381

COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)c(Br)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KAT7 O95251 20/20 1.00
▸ KAT6A Q92794 20/20 1.00
▸ KAT6B Q8WYB5 17/20 1.00
▸ KAT5 Q92993 10/20 1.00
▸ KAT8 Q9H7Z6 10/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22802469 1.00 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL32681110 0.92 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817444 0.92 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817399 0.90 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL32681127 0.90 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL26165869 0.90 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL26165844 0.89 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817386 0.87 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL32681101 0.86 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817421 0.86 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3986890-B9 BENZISOXAZOLE SULFONAMIDE DERIVATIVES PFIZER (US) 2025-04-16 — — EP disclosed
CN-114364672-B Benzisoxazole sulfonamide derivatives 辉瑞大药厂 2024-09-06 — — CN disclosed
EP-4299135-A2 BENZISOXAZOLE SULFONAMIDE DERIVATIVES Pfizer Inc. (US) 2024-01-03 — — EP disclosed
EP-3986890-B1 BENZISOXAZOLE SULFONAMIDE DERIVATIVES PFIZER (US) 2023-11-15 — — EP disclosed
EP-3986890-A1 BENZISOXAZOLE SULFONAMIDE DERIVATIVES Pfizer Inc. (US) 2022-04-27 — — EP disclosed
CN-114364672-A Benzisoxazole sulfonamide derivatives 辉瑞大药厂 2022-04-15 — — CN disclosed
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