Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT7 | O95251 | 10/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 10/20 | 0.45 |
| ▸ | KAT6B | Q8WYB5 | 7/20 | 0.45 |
| ▸ | KAT5 | Q92993 | 3/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22802414 | 1.00 | KAT7 (0.45) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL31432542 | 0.89 | KAT7 (0.36) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL31371951 | 0.88 | KAT7 (0.36) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL31432470 | 0.88 | KAT7 (0.36) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL31432516 | 0.88 | KAT7 (0.36) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL31432574 | 0.87 | KAT7 (0.38) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL31432519 | 0.86 | KAT7 (0.37) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25565517 | 0.81 | BRD4 (0.39) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL31371880 | 0.81 | GAA (0.39) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25214173 | 0.79 | KAT7 (0.39) | KAT7KAT6AKAT6BKAT5KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114364672-B | Benzisoxazole sulfonamide derivatives | 辉瑞大药厂 | 2024-09-06 | — | — | CN | disclosed |
| EP-3986890-A1 | BENZISOXAZOLE SULFONAMIDE DERIVATIVES | Pfizer Inc. (US) | 2022-04-27 | — | — | EP | disclosed |
| CN-114364672-A | Benzisoxazole sulfonamide derivatives | 辉瑞大药厂 | 2022-04-15 | — | — | CN | disclosed |