Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL29490683

O=C(O)C(F)(F)F.O=C(O)c1[nH]nnc1Oc1ccc2ncccc2c1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ HAO1 Q9UJM8 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL22608728 1.00 HAO1 (0.52) HAO1
SCHEMBL22815778 0.93 HAO1 (0.58) HAO1
Trifluoroacetic Acid SCHEMBL22608295 0.92 HAO1 (0.52) HAO1
Trifluoroacetic Acid SCHEMBL29490770 0.92 HAO1 (0.52) HAO1
Trifluoroacetic Acid SCHEMBL22608806 0.86 HAO1 (0.49) HAO1
Trifluoroacetic Acid SCHEMBL29490682 0.86 HAO1 (0.49) HAO1
Trifluoroacetic Acid SCHEMBL29514739 0.86 HAO1 (0.51) HAO1
Trifluoroacetic Acid SCHEMBL22807379 0.86 HAO1 (0.51) HAO1
SCHEMBL22608730 0.85 HAO1 (0.41) HAO1
SCHEMBL22815832 0.85 HAO1 (0.56) HAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3986863-A1 GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE BioMarin Pharmaceutical Inc. (US) 2022-04-27 — — EP disclosed
CN-114258390-A Glycolate oxidase inhibitors for disease treatment 生物马林药物股份有限公司 2022-03-29 — — CN disclosed
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