Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 8/20 | 1.00 |
| ▸ | CNR1 | P21554 | 1/20 | 0.61 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015149 | 1.00 | SERPINE1 (1.00) | SERPINE1CNR1GRIK1KDM4EHSD17B10 | |
| SCHEMBL1012706 | 0.89 | SERPINE1 (0.80) | SERPINE1CNR1GRIK1KDM4EHSD17B10 | |
| SCHEMBL1015090 | 0.88 | SERPINE1 (0.79) | SERPINE1CNR1GRIK1MEN1ALDH1A1 | |
| SCHEMBL1014817 | 0.86 | SERPINE1 (0.76) | SERPINE1CNR1GRIK1KDM4EHSD17B10 | |
| SCHEMBL29492572 | 0.86 | SERPINE1 (0.77) | SERPINE1CNR1GRIK1KDM4EHSD17B10 | |
| SCHEMBL1016107 | 0.86 | SERPINE1 (0.77) | SERPINE1CNR1GRIK1KDM4EHSD17B10 | |
| SCHEMBL22468222 | 0.85 | SERPINE1 (0.75) | SERPINE1CNR1GRIK1KDM4EHSD17B10 | |
| SCHEMBL1015517 | 0.84 | SERPINE1 (1.00) | SERPINE1CNR1KDM4EHSD17B10AKR1C4 | |
| SCHEMBL420979 | 0.83 | SERPINE1 (1.00) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL418577 | 0.81 | SERPINE1 (0.73) | SERPINE1CNR1KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025064449-A1 | TOPICAL COMPOSITIONS AND USES OF PAI-1 INHIBITORS | EIRION THERAPEUTICS, INC. (US) | 2025-03-27 | — | — | WO | claimed |
| US-20220105068-A1 | PLASMINOGEN ACTIVATOR INHIBITOR 1 (PAI-1) INHIBITORS AND USES THEREFOR | EIRION THERAPEUTICS, INC. | 2022-04-07 | — | — | US | claimed |
| WO-2025064449-A1 | TOPICAL COMPOSITIONS AND USES OF PAI-1 INHIBITORS | EIRION THERAPEUTICS, INC. (US) | 2025-03-27 | — | — | WO | disclosed |