Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 19/20 | 1.00 |
| ▸ | PIK3CA | P42336 | 17/20 | 1.00 |
| ▸ | MTOR | P42345 | 8/20 | 0.88 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.68 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.68 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.68 |
| ▸ | ATM | Q13315 | 2/20 | 0.68 |
| ▸ | CSF1R | P07333 | 1/20 | 0.68 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.68 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24270652 | 1.00 | PRKDC (1.00) | PRKDCPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL24270869 | 0.94 | PRKDC (1.00) | PRKDCPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL29492733 | 0.94 | PRKDC (1.00) | PRKDCPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL29492775 | 0.91 | PRKDC (1.00) | PRKDCPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL24270835 | 0.91 | PRKDC (1.00) | PRKDCPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL24270482 | 0.90 | PRKDC (1.00) | PRKDCPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL29492675 | 0.90 | PRKDC (1.00) | PRKDCPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL24270470 | 0.89 | PRKDC (0.93) | PRKDCPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL29492684 | 0.89 | PRKDC (0.93) | PRKDCPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL24270571 | 0.89 | PIK3CA (0.83) | PRKDCPIK3CAMTORPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669725-A | Novel aminopyridine and use thereof in the treatment of cancer | 奥克兰联合服务有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4217357-A1 | NOVEL AMINOPYRIDINES AND THEIR USE IN TREATING CANCER | Auckland Uniservices Limited (NZ) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022064430-A1 | NOVEL AMINOPYRIDINES AND THEIR USE IN TREATING CANCER | AUCKLAND UNISERVICES LIMITED (NZ) | 2022-03-31 | — | — | WO | disclosed |