SCHEMBL29496723

CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(N)=O)[C@@H](C)O

nearest known ligand 0.42

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	CRHR1	P34998	1/20	0.41

▸	CRHR2	Q13324	1/20	0.41

▸	FURIN	P09958	1/20	0.40

▸	MC4R	P32245	1/20	0.39

▸	GLP1R	P43220	2/20	0.39

▸	SCTR	P47872	1/20	0.39

▸	NPY4R	P50391	3/20	0.38

▸	NPY2R	P49146	3/20	0.38

▸	NPY1R	P25929	2/20	0.38

▸	NPY5R	Q15761	2/20	0.38

▸	STAT3	P40763	3/20	0.38

▸	GCGR	P47871	1/20	0.38

▸	GHSR	Q92847	2/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30939707	0.95	MC4R (0.40)	CRHR1CRHR2MC4RGLP1RSCTR
SCHEMBL30904413	0.87	BACE1 (0.45)	CRHR1CRHR2GLP1RSCTR
SCHEMBL29937026	0.85	ERAP2 (0.46)	NPY4RNPY2RNPY1RNPY5R
SCHEMBL31472846	0.85	ERAP2 (0.43)	MC4RNPY4RNPY2RNPY1R
SCHEMBL31472847	0.85	ERAP2 (0.43)	MC4RNPY4RNPY2RNPY1R
SCHEMBL31588088	0.84	GLP1R (0.49)	GLP1RSCTRNPY4RNPY2RNPY1R
SCHEMBL30512656	0.84	BACE1 (0.45)	CRHR1CRHR2
SCHEMBL30906004	0.84	ERAP2 (0.44)	NPY4RNPY2RNPY1RNPY5R
SCHEMBL29937046	0.84	ERAP2 (0.47)	NPY4RNPY2RNPY1RNPY5R
SCHEMBL29937022	0.84	ERAP2 (0.47)	NPY4RNPY2RNPY1RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20220088113-A1	SPECIFIC PEPTIDE CLATHRIN INHIBITORS	KOTIN, Oleg Arkadyevich (RU)	2022-03-24	—	—	US	disclosed