Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.64 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.64 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.64 |
| ▸ | TNF | P01375 | 2/20 | 0.64 |
| ▸ | IL1B | P01584 | 2/20 | 0.64 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.64 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14998787 | 1.00 | CRBN (0.64) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL20783221 | 0.91 | CRBN (0.66) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL19037562 | 0.88 | CRBN (0.61) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL2174826 | 0.84 | CRBN (0.61) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL30830400 | 0.84 | CRBN (0.61) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL4389404 | 0.82 | CRBN (0.71) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL4384072 | 0.82 | CRBN (0.71) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL4311585 | 0.82 | CRBN (0.71) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL14998788 | 0.82 | DDB1 (0.67) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL26051925 | 0.81 | CRBN (0.81) | CRBNDDB1IKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116419922-B | Method for selectively synthesizing 3,6' -dithiopomalidomide from pomalidomide | 艾维斯生物株式会社 | 2025-05-02 | — | — | CN | disclosed |
| WO-2022092774-A1 | METHOD FOR SELECTIVELY SYNTHESIZING 3,6'-DITHIOPOMALIDOMIDE FROM POMALIDOMIDE | 주식회사 아이비스바이오 | 2022-05-05 | — | — | WO | disclosed |