Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 19/20 | 0.69 |
| ▸ | CCNT1 | O60563 | 18/20 | 0.69 |
| ▸ | CDK9 | P50750 | 18/20 | 0.69 |
| ▸ | CDK12 | Q9NYV4 | 18/20 | 0.69 |
| ▸ | CDK7 | P50613 | 6/20 | 0.69 |
| ▸ | CCNH | P51946 | 6/20 | 0.69 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.69 |
| ▸ | CDK2 | P24941 | 16/20 | 0.57 |
| ▸ | CCNE1 | P24864 | 15/20 | 0.57 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.53 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29498437 | 0.91 | CCNK (0.57) | CCNKCCNT1CDK9CDK12CDK7 | |
| SCHEMBL29492509 | 0.90 | CCNK (0.63) | CCNKCCNT1CDK9CDK12CDK7 | |
| SCHEMBL27121866 | 0.90 | CCNK (0.63) | CCNKCCNT1CDK9CDK12CDK7 | |
| SCHEMBL25593261 | 0.90 | CCNK (0.63) | CCNKCCNT1CDK9CDK12CDK7 | |
| SCHEMBL21178818 | 0.87 | CCNK (0.57) | CCNKCCNT1CDK9CDK12CDK7 | |
| SCHEMBL29498434 | 0.86 | CCNT1 (0.62) | CCNKCCNT1CDK9CDK12CDK7 | |
| SCHEMBL29498417 | 0.85 | CCNK (0.54) | CCNKCCNT1CDK9CDK12CDK7 | |
| SCHEMBL29498415 | 0.85 | CCNT1 (0.70) | CCNKCCNT1CDK9CDK12CDK7 | |
| SCHEMBL21178843 | 0.84 | CCNK (0.59) | CCNKCCNT1CDK9CDK12CDK7 | |
| SCHEMBL29498465 | 0.84 | CDK7 (0.54) | CCNKCCNT1CDK9CDK12CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063212-A1 | PYRIMIDYL DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 广州费米子科技有限责任公司 | 2022-03-31 | — | — | WO | disclosed |