Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.33 |
| ▸ | PDE8B | O95263 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5626676 | 0.90 | — | — | |
| SCHEMBL15941616 | 0.89 | MAPT (0.33) | DHFR | |
| SCHEMBL17352600 | 0.85 | KDM4E (0.38) | — | |
| SCHEMBL2954548 | 0.84 | KDM4E (0.40) | — | |
| SCHEMBL2950064 | 0.84 | HRH3 (0.36) | PTPN1 | |
| SCHEMBL2953203 | 0.82 | PDE8B (0.34) | PDE8B | |
| SCHEMBL2952916 | 0.81 | — | — | |
| SCHEMBL28301992 | 0.77 | PARP1 (0.43) | — | |
| SCHEMBL2954019 | 0.75 | — | — | |
| SCHEMBL17262847 | 0.75 | PDE8B (0.36) | DHFRPDE8B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |