Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21640519 | 0.85 | KDM1A (0.44) | KDM4ENPY5RKDM1AMAOAMAOB | |
| SCHEMBL22614345 | 0.84 | NPY5R (0.48) | NPY5RKDM1AMAOAMAOBTSHR | |
| SCHEMBL22614348 | 0.84 | NPY5R (0.48) | NPY5RKDM1AMAOAMAOBTSHR | |
| SCHEMBL13393188 | 0.82 | KDM1A (0.43) | KDM4ENPY5RKDM1AMAOAMAOB | |
| SCHEMBL30524731 | 0.81 | HTR2C (0.54) | KDM4EHDAC1KDM1AMAOAMAOB | |
| SCHEMBL27470365 | 0.81 | NPY5R (0.46) | KDM4ENPC1RAB9ANPY5RKDM1A | |
| SCHEMBL5534711 | 0.80 | HDAC6 (0.66) | HPGDHDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL29409097 | 0.79 | NPY5R (0.48) | NPY5RKDM1AMAOBALDH1A1KMT2A | |
| SCHEMBL28719953 | 0.79 | NPY5R (0.48) | NPY5RKDM1AMAOBALDH1A1KMT2A | |
| SCHEMBL28719954 | 0.79 | NPY5R (0.48) | NPY5RKDM1AMAOBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206848-A | Substituted cycloalkyl compounds as modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2022-03-18 | — | — | CN | disclosed |