SCHEMBL29501082

SCHEMBL29501082

CC(C)(C)c1ccc2c(c1)C1(c3ccccc3-c3ccc(Cl)cc31)c1cc(Br)ccc1-2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 12/20 0.43
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
PLA2G1B P04054 1/20 0.38
NFKB1 P19838 1/20 0.38
CASP3 P42574 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
AKR1A1 P14550 1/20 0.36
AKR1B1 P15121 1/20 0.36
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
OPRM1 P35372 1/20 0.32
OPRD1 P41143 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23485172 1.00 PDK2 (0.43) PDK2NPC1ALDH1A1PLA2G1BNFKB1
SCHEMBL23485173 1.00 PDK2 (0.43) PDK2NPC1ALDH1A1PLA2G1BNFKB1
SCHEMBL23485174 0.93 PDK2 (0.39) PDK2NPC1ALDH1A1PLA2G1BNFKB1
SCHEMBL21881099 0.92 PDK2 (0.49) PDK2NPC1ALDH1A1PLA2G1BNFKB1
SCHEMBL3885909 0.92 PDK2 (0.49) PDK2NPC1ALDH1A1PLA2G1BNFKB1
SCHEMBL22744936 0.92 PDK2 (0.49) PDK2NPC1ALDH1A1PLA2G1BNFKB1
SCHEMBL29456661 0.92 PDK2 (0.49) PDK2NPC1ALDH1A1PLA2G1BNFKB1
SCHEMBL22106372 0.87 PDK2 (0.49) PDK2L3MBTL1AKR1A1AKR1B1OPRM1
SCHEMBL21922833 0.87 PDK2 (0.49) PDK2L3MBTL1AKR1A1AKR1B1OPRM1
SCHEMBL29501064 0.87 PDK2 (0.49) PDK2L3MBTL1AKR1A1AKR1B1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114380803-B Spirobifluorene compound, electron transport composition, and organic electroluminescent device 常州强力电子新材料股份有限公司 2024-07-12 CN disclosed
CN-114380803-A Spirobifluorene compound, electron transport composition and organic electroluminescent device 常州强力昱镭光电材料有限公司 2022-04-22 CN disclosed