Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 20/20 | 0.60 |
| ▸ | WDR77 | Q9BQA1 | 18/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26247741 | 1.00 | PRMT5 (0.60) | PRMT5WDR77 | |
| SCHEMBL26247866 | 1.00 | PRMT5 (0.60) | PRMT5WDR77 | |
| SCHEMBL29501355 | 1.00 | PRMT5 (0.60) | PRMT5WDR77 | |
| SCHEMBL29501446 | 1.00 | PRMT5 (0.60) | PRMT5WDR77 | |
| SCHEMBL25389789 | 1.00 | PRMT5 (0.60) | PRMT5WDR77 | |
| SCHEMBL25385695 | 1.00 | PRMT5 (0.60) | PRMT5WDR77 | |
| SCHEMBL25387714 | 0.91 | PRMT5 (0.50) | PRMT5WDR77 | |
| SCHEMBL25386006 | 0.90 | PRMT5 (0.62) | PRMT5WDR77 | |
| SCHEMBL30493050 | 0.90 | PRMT5 (0.62) | PRMT5WDR77 | |
| SCHEMBL26251193 | 0.90 | PRMT5 (0.62) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022048631-A1 | COMPOUND HAVING ANTITUMOR ACTIVITY AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-03-10 | — | — | WO | disclosed |