Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 20/20 | 0.64 |
| ▸ | TTK | P33981 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.57 |
| ▸ | CSF1R | P07333 | 1/20 | 0.57 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.57 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23948473 | 0.94 | PRKDC (0.69) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL29501951 | 0.92 | PRKDC (0.61) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL29502093 | 0.89 | PRKDC (0.71) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL23948123 | 0.89 | PRKDC (0.71) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL23948125 | 0.88 | PRKDC (0.61) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL23948196 | 0.87 | PRKDC (0.60) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL29501989 | 0.86 | PRKDC (0.58) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL23948539 | 0.86 | PRKDC (0.58) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL25057401 | 0.85 | PRKDC (0.74) | PRKDCTTKKCNH2CSF1RPIK3CA | |
| SCHEMBL29282659 | 0.84 | PRKDC (0.55) | PRKDCTTKKCNH2PIK3CDCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315834-B | Imidazolone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-114315834-A | Imidazolidinone derivatives and their use in medicaments | 成都百裕制药股份有限公司 | 2022-04-12 | — | — | CN | disclosed |