SCHEMBL29501933

SCHEMBL29501933

Cc1cc(C(N)=O)c(F)cc1Nc1ncc2c(n1)n(C1C3CCC1CC(O)C3)c(=O)n2C

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 20/20 0.51
TTK P33981 5/20 0.50
CSF1R P07333 2/20 0.50
KCNH2 Q12809 4/20 0.48
AURKA O14965 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23925127 1.00 PRKDC (0.51) PRKDCTTKCSF1RKCNH2AURKA
SCHEMBL23948604 0.91 PRKDC (0.53) PRKDCTTKCSF1RKCNH2AURKA
SCHEMBL23948560 0.91 PRKDC (0.53) PRKDCTTKCSF1RKCNH2AURKA
SCHEMBL26159815 0.90 PRKDC (0.56) PRKDCTTKCSF1RKCNH2AURKA
SCHEMBL26159808 0.90 PRKDC (0.56) PRKDCTTKCSF1RKCNH2AURKA
SCHEMBL23948149 0.90 PRKDC (0.56) PRKDCTTKCSF1RKCNH2AURKA
SCHEMBL23948133 0.88 PRKDC (0.60) PRKDCTTKCSF1RKCNH2
SCHEMBL23948529 0.88 PRKDC (0.66) PRKDCTTKCSF1RKCNH2
SCHEMBL23948157 0.87 PRKDC (0.55) PRKDCTTKCSF1RKCNH2AURKA
SCHEMBL23618784 0.86 PRKDC (0.44) PRKDCTTKCSF1RKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315834-B Imidazolone derivatives and their use in medicine 成都百裕制药股份有限公司 2024-01-05 CN disclosed
CN-114315834-A Imidazolidinone derivatives and their use in medicaments 成都百裕制药股份有限公司 2022-04-12 CN disclosed