SCHEMBL29501959

SCHEMBL29501959

Cn1c(=O)n(C2C3CCC2CC(O)C3)c2nc(Cl)ncc21

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 14/20 0.43
TTK P33981 3/20 0.39
CSF1R P07333 2/20 0.39
PIK3CA P42336 7/20 0.36
MTOR P42345 6/20 0.36
KCNH2 Q12809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23620421 1.00 PRKDC (0.43) PRKDCTTKCSF1RPIK3CAMTOR
SCHEMBL23948559 0.87 PRKDC (0.47) PRKDCTTKCSF1RPIK3CAMTOR
SCHEMBL23948235 0.87 PRKDC (0.47) PRKDCTTKCSF1RPIK3CAMTOR
SCHEMBL24963661 0.87 PRKDC (0.40) PRKDCTTKCSF1RPIK3CAMTOR
SCHEMBL29501993 0.85 PRKDC (0.38) PRKDCTTKCSF1RPIK3CAKCNH2
SCHEMBL23620422 0.85 PRKDC (0.38) PRKDCTTKCSF1RPIK3CAKCNH2
SCHEMBL29502052 0.85 PRKDC (0.49) PRKDCTTKCSF1RPIK3CAMTOR
SCHEMBL23620537 0.85 PRKDC (0.49) PRKDCTTKCSF1RPIK3CAMTOR
SCHEMBL23625348 0.82 PRKDC (0.54) PRKDCTTKCSF1RPIK3CAMTOR
SCHEMBL23452636 0.81 PRKDC (0.62) PRKDCTTKCSF1RPIK3CAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315834-B Imidazolone derivatives and their use in medicine 成都百裕制药股份有限公司 2024-01-05 CN disclosed
CN-113121538-B Furan derivative and application thereof in medicine 成都百裕制药股份有限公司 2023-04-21 CN disclosed
CN-114315834-A Imidazolidinone derivatives and their use in medicaments 成都百裕制药股份有限公司 2022-04-12 CN disclosed