Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 20/20 | 0.66 |
| ▸ | TTK | P33981 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.59 |
| ▸ | CSF1R | P07333 | 1/20 | 0.59 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23948711 | 1.00 | PRKDC (0.66) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL23948194 | 0.93 | PRKDC (0.67) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL29501967 | 0.93 | PRKDC (0.67) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL23948215 | 0.91 | PRKDC (0.65) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL23948201 | 0.89 | PRKDC (0.70) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL29501883 | 0.89 | PRKDC (0.70) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL23948211 | 0.88 | PRKDC (0.69) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL23948189 | 0.88 | PRKDC (0.69) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL23948132 | 0.87 | PRKDC (0.68) | PRKDCTTKKCNH2PIK3CDCSF1R | |
| SCHEMBL29502012 | 0.87 | PRKDC (0.68) | PRKDCTTKKCNH2PIK3CDCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315834-B | Imidazolone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-114315834-A | Imidazolidinone derivatives and their use in medicaments | 成都百裕制药股份有限公司 | 2022-04-12 | — | — | CN | disclosed |