SCHEMBL29502010

SCHEMBL29502010

Cc1cc(C(=O)N2CCOCC2)ccc1Nc1ncc2c(n1)n(C1CCOCC1)c(=O)n2C

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 20/20 0.67
TTK P33981 3/20 0.61
CSF1R P07333 2/20 0.61
KCNH2 Q12809 1/20 0.61
PIK3CD O00329 1/20 0.61
PIK3R1 P27986 1/20 0.61
PIK3CA P42336 1/20 0.61
PIK3CB P42338 1/20 0.61
MTOR P42345 1/20 0.61
PIK3CG P48736 1/20 0.61
ATM Q13315 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23948180 1.00 PRKDC (0.67) PRKDCTTKCSF1RKCNH2PIK3CD
SCHEMBL26160139 0.96 PRKDC (0.66) PRKDCTTKCSF1RKCNH2PIK3CD
SCHEMBL23948184 0.91 PRKDC (0.63) PRKDCTTKCSF1RKCNH2PIK3CD
SCHEMBL29502120 0.90 PRKDC (0.71) PRKDCTTKCSF1RKCNH2PIK3CD
SCHEMBL23948124 0.90 PRKDC (0.71) PRKDCTTKCSF1RKCNH2PIK3CD
SCHEMBL23948113 0.89 PRKDC (0.70) PRKDCTTKCSF1RKCNH2PIK3CD
SCHEMBL29502089 0.88 PRKDC (0.69) PRKDCTTKCSF1RKCNH2PIK3CD
SCHEMBL23948206 0.88 PRKDC (0.69) PRKDCTTKCSF1RKCNH2PIK3CD
SCHEMBL29502134 0.88 PRKDC (0.68) PRKDCTTKCSF1RKCNH2PIK3CD
SCHEMBL23948197 0.88 PRKDC (0.68) PRKDCTTKCSF1RKCNH2PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315834-B Imidazolone derivatives and their use in medicine 成都百裕制药股份有限公司 2024-01-05 CN disclosed
CN-114315834-A Imidazolidinone derivatives and their use in medicaments 成都百裕制药股份有限公司 2022-04-12 CN disclosed