Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK3 | O43781 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.59 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.59 |
| ▸ | PRKACA | P17612 | 1/20 | 0.59 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.59 |
| ▸ | MARK3 | P27448 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 1/20 | 0.59 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.59 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.59 |
| ▸ | CLK2 | P49760 | 1/20 | 0.59 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.59 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.59 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.59 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.59 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.59 |
| ▸ | MELK | Q14680 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3782622 | 1.00 | DYRK3 (0.59) | DYRK3ROCK2PRKD3MAP4K4PHKG2 | |
| SCHEMBL16236518 | 0.87 | DYRK3 (0.57) | DYRK3ROCK2PRKD3MAP4K4PHKG2 | |
| SCHEMBL16236495 | 0.83 | DYRK3 (0.67) | DYRK3ROCK2PRKD3MAP4K4PHKG2 | |
| SCHEMBL31568623 | 0.83 | DYRK3 (0.56) | DYRK3ROCK2PRKD3MAP4K4PHKG2 | |
| SCHEMBL16236954 | 0.83 | DYRK3 (0.56) | DYRK3ROCK2PRKD3MAP4K4PHKG2 | |
| SCHEMBL23966679 | 0.81 | DYRK3 (0.60) | DYRK3ROCK2PRKD3MAP4K4PHKG2 | |
| SCHEMBL16236958 | 0.81 | DYRK3 (0.60) | DYRK3ROCK2PRKD3MAP4K4PHKG2 | |
| SCHEMBL16236628 | 0.80 | FLT3 (0.53) | DYRK3ROCK2PRKD3MAP4K4PHKG2 | |
| SCHEMBL23966776 | 0.80 | DYRK3 (0.56) | DYRK3ROCK2PRKD3MAP4K4PHKG2 | |
| SCHEMBL16236364 | 0.80 | FLT3 (0.53) | DYRK3ROCK2PRKD3MAP4K4PHKG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110194772-B | Alkynyl (hetero) aromatic ring compounds for inhibiting protein kinase activity | 深圳市塔吉瑞生物医药有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-109311894-B | N- (substituted-phenyl) -sulfonamide derivatives as kinase inhibitors | 内尔维阿诺医学科学有限公司 | 2022-03-22 | — | — | CN | disclosed |