SCHEMBL29503500

SCHEMBL29503500

Cn1cc(-c2cccc(NS(=O)(=O)c3ccc(Br)cc3F)c2F)c2c(N)ncnc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EIF2AK3 Q9NZJ5 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19743655 1.00 EIF2AK3 (1.00) EIF2AK3
SCHEMBL29503504 0.89 EIF2AK3 (0.81) EIF2AK3
SCHEMBL19743305 0.89 EIF2AK3 (1.00) EIF2AK3
SCHEMBL29503502 0.89 EIF2AK3 (1.00) EIF2AK3
SCHEMBL19743299 0.89 EIF2AK3 (0.81) EIF2AK3
SCHEMBL19743666 0.87 EIF2AK3 (0.80) EIF2AK3
SCHEMBL29503423 0.86 EIF2AK3 (0.84) EIF2AK3
SCHEMBL21084179 0.86 EIF2AK3 (0.84) EIF2AK3
SCHEMBL21084172 0.85 EIF2AK3 (1.00) EIF2AK3
SCHEMBL29503506 0.85 EIF2AK3 (1.00) EIF2AK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311894-B N- (substituted-phenyl) -sulfonamide derivatives as kinase inhibitors 内尔维阿诺医学科学有限公司 2022-03-22 CN disclosed