SCHEMBL29503519

SCHEMBL29503519

Cn1cc(-c2cccc(NS(=O)(=O)c3ccc(O)c(Cl)c3)c2F)c2c(N)ncnc21

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EIF2AK3 Q9NZJ5 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19743585 1.00 EIF2AK3 (0.85) EIF2AK3
SCHEMBL21084212 0.92 EIF2AK3 (1.00) EIF2AK3
SCHEMBL29503523 0.92 EIF2AK3 (1.00) EIF2AK3
SCHEMBL29503388 0.88 EIF2AK3 (1.00) EIF2AK3
SCHEMBL19743304 0.88 EIF2AK3 (1.00) EIF2AK3
SCHEMBL19743311 0.88 EIF2AK3 (0.88) EIF2AK3
SCHEMBL21084185 0.87 EIF2AK3 (0.84) EIF2AK3
SCHEMBL21084209 0.87 EIF2AK3 (0.85) EIF2AK3
SCHEMBL29503464 0.87 EIF2AK3 (0.85) EIF2AK3
SCHEMBL21084199 0.87 EIF2AK3 (1.00) EIF2AK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311894-B N- (substituted-phenyl) -sulfonamide derivatives as kinase inhibitors 内尔维阿诺医学科学有限公司 2022-03-22 CN disclosed