SCHEMBL29506801

SCHEMBL29506801

C[C@H]1C2N(C(=O)CN(C)N2C(=O)NCc2ccccc2)[C@@H](Cc2ccc(O)cc2)C(=O)N1Cc1cccc2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 3/20 0.67
TCF4 P15884 2/20 0.67
CREBBP Q92793 2/20 0.67
TCF7 P36402 2/20 0.56
CLPP Q16740 2/20 0.56
BCL9 O00512 1/20 0.56
CYP3A4 P08684 16/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15962638 1.00 CTNNB1 (0.67) CTNNB1TCF4CREBBPTCF7CLPP
SCHEMBL15960519 1.00 CTNNB1 (0.67) CTNNB1TCF4CREBBPTCF7CLPP
SCHEMBL1591177 1.00 CTNNB1 (0.67) CTNNB1TCF4CREBBPTCF7CLPP
SCHEMBL15309304 0.97 CTNNB1 (0.63) CTNNB1TCF4CREBBPTCF7CLPP
SCHEMBL15309547 0.95 CTNNB1 (0.61) CTNNB1TCF4CREBBPTCF7CLPP
SCHEMBL15309477 0.94 CTNNB1 (0.64) CTNNB1TCF4CREBBPTCF7CLPP
SCHEMBL15309631 0.93 CTNNB1 (0.59) CTNNB1TCF4CREBBPTCF7CLPP
SCHEMBL29506800 0.93 CTNNB1 (0.65) CTNNB1TCF4CREBBPTCF7CLPP
SCHEMBL1591567 0.93 CTNNB1 (0.65) CTNNB1TCF4CREBBPTCF7CLPP
SCHEMBL16966310 0.92 CTNNB1 (0.65) CTNNB1TCF4CREBBPTCF7CLPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117083065-A Novel treatment and prevention of sarcopenia-related diseases and the like 庆应义塾 2023-11-17 CN disclosed
EP-4238567-A1 NOVEL TREATMENT AND PREVENTION OF SARCOPENIA-RELATED DISEASES Keio University (JP) 2023-09-06 EP disclosed
WO-2022092294-A1 NOVEL TREATMENT AND PREVENTION OF SARCOPENIA-RELATED DISEASES 学校法人慶應義塾 2022-05-05 WO disclosed