Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | NMUR2 | Q9GZQ4 | 6/20 | 0.49 |
| ▸ | NMUR1 | Q9HB89 | 6/20 | 0.49 |
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.45 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506913 | 0.97 | MAPK8 (0.50) | MAPK8MAPK9MAPK10SLC6A2NMUR2 | |
| SCHEMBL29506914 | 0.96 | MAPK8 (0.51) | MAPK8MAPK9MAPK10SLC6A2NMUR2 | |
| SCHEMBL29601373 | 0.93 | MAPK8 (0.52) | MAPK8MAPK9MAPK10SLC6A2NMUR2 | |
| SCHEMBL31049835 | 0.91 | MAPK8 (0.48) | MAPK8MAPK9MAPK10SLC6A2NMUR2 | |
| SCHEMBL29634954 | 0.90 | CALCRL (0.51) | MAPK8MAPK9MAPK10NMUR2NMUR1 | |
| SCHEMBL31049840 | 0.89 | MAPK8 (0.47) | MAPK8MAPK9MAPK10SLC6A2NMUR2 | |
| SCHEMBL31049845 | 0.89 | MAPK8 (0.45) | MAPK8MAPK9MAPK10NMUR2NMUR1 | |
| SCHEMBL31049843 | 0.88 | MAPK8 (0.43) | MAPK8MAPK9MAPK10SLC6A2NMUR2 | |
| SCHEMBL31490515 | 0.88 | MAPK8 (0.54) | MAPK8MAPK9MAPK10SLC6A2NMUR2 | |
| SCHEMBL31490504 | 0.87 | MAPK8 (0.52) | MAPK8MAPK9MAPK10SLC6A2NMUR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955620-A | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118930608-A | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-114341158-B | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-114341158-A | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2022-04-12 | — | — | CN | disclosed |