Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9947842 | 0.80 | BDKRB1 (0.70) | BDKRB1 | |
| SCHEMBL9947952 | 0.80 | BDKRB1 (0.57) | BDKRB1 | |
| SCHEMBL2951653 | 0.80 | BDKRB1 (0.57) | BDKRB1 | |
| SCHEMBL3110911 | 0.79 | BDKRB1 (0.67) | BDKRB1 | |
| Hydrochloric Acid SCHEMBL2949311 | 0.79 | BDKRB1 (0.56) | BDKRB1 | |
| SCHEMBL13213788 | 0.77 | BDKRB1 (0.68) | BDKRB1 | |
| SCHEMBL13214059 | 0.77 | BDKRB1 (0.73) | BDKRB1 | |
| SCHEMBL2941691 | 0.76 | BDKRB1 (0.46) | BDKRB1 | |
| SCHEMBL13214051 | 0.76 | BDKRB1 (0.65) | BDKRB1 | |
| SCHEMBL13214182 | 0.75 | BDKRB1 (0.64) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396301-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | Jerini AG (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091876-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | JERINI AG (DE) | 2010-08-19 | — | — | WO | disclosed |
| US-20070189865-A1 | Amino cyclopropane carboxamide derivatives as bradykinin antagonists | MERCK & CO., INC. | 2007-08-16 | — | — | US | disclosed |
| EP-1723143-A2 | AMINO CYCLOPROPANE CARBOXAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | Merck & Co., Inc. (US) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005085198-A2 | AMINO CYCLOPROPANE CARBOXAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | MERCK & CO., INC. (US) | 2005-09-15 | — | — | WO | disclosed |