Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.60 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HRH2 | P25021 | 1/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22761521 | 1.00 | TLR7 (0.60) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL22761522 | 1.00 | TLR7 (0.60) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL22761539 | 1.00 | TLR7 (0.60) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL22761516 | 0.90 | TLR7 (0.61) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL22749244 | 0.90 | TLR7 (0.57) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL22749245 | 0.90 | TLR7 (0.57) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL22749231 | 0.90 | TLR7 (0.61) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL22749241 | 0.90 | TLR7 (0.61) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL22761523 | 0.90 | TLR7 (0.57) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL29508413 | 0.90 | TLR7 (0.57) | TLR7NUDT1LMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980415-A1 | N-1 BRANCHED ALKYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS | 3M Innovative Properties Company (US) | 2022-04-13 | — | — | EP | disclosed |