Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28681620 | 1.00 | KCNH2 (0.38) | KCNH2LRRK2CACNA2D1TLR7TLR8 | |
| SCHEMBL28674921 | 0.93 | TLR8 (0.41) | KCNH2LRRK2CACNA2D1TLR7TLR8 | |
| SCHEMBL29508394 | 0.93 | TLR8 (0.41) | KCNH2LRRK2CACNA2D1TLR7TLR8 | |
| SCHEMBL22749304 | 0.90 | LRRK2 (0.39) | LRRK2TLR7MEN1PKMKMT2A | |
| SCHEMBL22749302 | 0.90 | LRRK2 (0.39) | LRRK2TLR7MEN1PKMKMT2A | |
| SCHEMBL22749276 | 0.86 | LRRK2 (0.40) | LRRK2MEN1PKMKMT2A | |
| SCHEMBL22749275 | 0.86 | LRRK2 (0.40) | LRRK2MEN1PKMKMT2A | |
| SCHEMBL21994851 | 0.85 | KMT2A (0.37) | LRRK2TLR7TLR8MEN1PKM | |
| SCHEMBL21994850 | 0.85 | KMT2A (0.37) | LRRK2TLR7TLR8MEN1PKM | |
| SCHEMBL28693066 | 0.85 | LRRK2 (0.38) | LRRK2TLR7TLR8MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980415-A1 | N-1 BRANCHED ALKYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS | 3M Innovative Properties Company (US) | 2022-04-13 | — | — | EP | disclosed |