Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22749326 | 1.00 | MAPT (0.37) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL22749325 | 1.00 | MAPT (0.37) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL22749267 | 0.94 | MAPT (0.36) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL22749268 | 0.94 | MAPT (0.36) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL29508422 | 0.94 | MAPT (0.36) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL29508411 | 0.91 | MAPT (0.40) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL22749316 | 0.91 | MAPT (0.40) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL22749318 | 0.91 | MAPT (0.40) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL22749265 | 0.88 | MAPT (0.38) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL22749266 | 0.88 | MAPT (0.38) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980415-A1 | N-1 BRANCHED ALKYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS | 3M Innovative Properties Company (US) | 2022-04-13 | — | — | EP | disclosed |