Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.41 |
| ▸ | DRD3 | P35462 | 9/20 | 0.41 |
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | MLNR | O43193 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4106625 | 0.92 | HTR1D (0.51) | DRD2DRD3HTR6HTR2AHTR2C | |
| SCHEMBL4106767 | 0.92 | HTR1D (0.51) | DRD2DRD3HTR6HTR2AHTR2C | |
| SCHEMBL4101568 | 0.92 | HTR1D (0.51) | DRD2DRD3HTR6HTR2AHTR2C | |
| SCHEMBL4106772 | 0.92 | HTR1D (0.51) | DRD2DRD3HTR6HTR2AHTR2C | |
| SCHEMBL4101572 | 0.92 | HTR1D (0.51) | DRD2DRD3HTR6HTR2AHTR2C | |
| SCHEMBL1545326 | 0.90 | TRIM24 (0.46) | DRD2DRD3HTR6HTR2AHTR2C | |
| SCHEMBL1546368 | 0.90 | TRIM24 (0.46) | DRD2DRD3HTR6HTR2AHTR2C | |
| SCHEMBL1545323 | 0.90 | TRIM24 (0.46) | DRD2DRD3HTR6HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL1546028 | 0.89 | TRIM24 (0.45) | DRD2DRD3HTR6HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL1546025 | 0.89 | TRIM24 (0.45) | DRD2DRD3HTR6HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759397-B2 | 6-amino(aza)indane compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor | ABBOTT GMBH & CO. KG (DE) | 2010-07-20 | — | — | US | claimed |