Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21435672 | 1.00 | DHODH (0.75) | DHODH | |
| SCHEMBL20107686 | 1.00 | DHODH (0.75) | DHODH | |
| SCHEMBL21853474 | 0.96 | DHODH (0.69) | DHODH | |
| SCHEMBL20107899 | 0.96 | DHODH (0.69) | DHODH | |
| SCHEMBL29816423 | 0.96 | DHODH (0.69) | DHODH | |
| SCHEMBL29816463 | 0.93 | DHODH (0.66) | DHODH | |
| SCHEMBL20107662 | 0.93 | DHODH (0.66) | DHODH | |
| SCHEMBL21853496 | 0.93 | DHODH (0.64) | DHODH | |
| SCHEMBL20107966 | 0.93 | DHODH (0.64) | DHODH | |
| SCHEMBL29513015 | 0.93 | DHODH (0.64) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041714-A1 | BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS | Janssen Biotech, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-110023302-B | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2022-07-26 | — | — | CN | disclosed |
| EP-4021886-A1 | SUBSTITUTED UREA DIHYDROOROTATE DEHYDROGENASE INHIBITORS | Janssen Biotech, Inc. (US) | 2022-07-06 | — | — | EP | disclosed |
| CN-114286813-A | Substituted urea dihydroorotate dehydrogenase inhibitors | 詹森生物科技公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-110248937-B | 4, 5-Cyclic 1,2, 4-triazolones | 拜耳股份有限公司 | 2022-03-29 | — | — | CN | disclosed |