Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1868872 | 0.91 | DPP4 (0.68) | DPP4TAAR1ADRA2CHTR2AMAOB | |
| Boric Acid SCHEMBL28704755 | 0.84 | DPP4 (0.59) | DPP4TAAR1ADRA2CHTR2AMAOB | |
| SCHEMBL27670027 | 0.83 | DPP4 (0.83) | DPP4TAAR1CYP2A6LOXL2TP53 | |
| Boric Acid SCHEMBL29044400 | 0.81 | DPP4 (0.55) | DPP4TAAR1ADRA2CHTR2AMAOB | |
| Hydrochloric Acid SCHEMBL29502692 | 0.81 | DPP4 (0.79) | DPP4TAAR1CYP2A6TP53MAPK1 | |
| Hydrogen Sulfide SCHEMBL27639875 | 0.81 | DPP4 (0.79) | DPP4TAAR1CYP2A6LOXL2TP53 | |
| SCHEMBL31026930 | 0.80 | DPP4 (0.48) | DPP4ADRA2CCYP2A6TP53MAPK1 | |
| SCHEMBL27525656 | 0.80 | DPP4 (0.53) | DPP4TAAR1ADRA2CHTR2AMAOB | |
| SCHEMBL13685146 | 0.79 | DPP4 (0.47) | DPP4CYP2A6SMN1; SMN2MAPK1 | |
| SCHEMBL9839608 | 0.79 | TAAR1 (0.52) | DPP4TAAR1ADRA2CHTR2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110248937-B | 4, 5-Cyclic 1,2, 4-triazolones | 拜耳股份有限公司 | 2022-03-29 | — | — | CN | disclosed |