Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 12/20 | 0.76 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.73 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.65 |
| ▸ | THRB | P10828 | 4/20 | 0.65 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.49 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.49 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.49 |
| ▸ | CSNK1A1L | Q8N752 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26720633 | 1.00 | CSNK1D (0.76) | CSNK1DMAPK14TGFBR1THRBCSNK1A1 | |
| SCHEMBL29513136 | 0.97 | CSNK1D (0.75) | CSNK1DMAPK14TGFBR1THRBCSNK1A1 | |
| SCHEMBL26720639 | 0.97 | CSNK1D (0.75) | CSNK1DMAPK14TGFBR1THRBCSNK1A1 | |
| SCHEMBL29513212 | 0.87 | CSNK1D (0.57) | CSNK1DMAPK14TGFBR1THRB | |
| SCHEMBL26720717 | 0.87 | CSNK1D (0.57) | CSNK1DMAPK14TGFBR1THRB | |
| SCHEMBL29513204 | 0.86 | CSNK1D (1.00) | CSNK1DMAPK14TGFBR1THRBCSNK1A1 | |
| SCHEMBL26720722 | 0.86 | CSNK1D (1.00) | CSNK1DMAPK14TGFBR1THRBCSNK1A1 | |
| SCHEMBL26720720 | 0.85 | CSNK1D (0.58) | CSNK1DMAPK14TGFBR1THRBCSNK1A1 | |
| SCHEMBL29513162 | 0.85 | CSNK1D (0.58) | CSNK1DMAPK14TGFBR1THRBCSNK1A1 | |
| SCHEMBL29513352 | 0.85 | CSNK1D (1.00) | CSNK1DMAPK14TGFBR1THRBCSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214214-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-07-26 | — | — | EP | claimed |
| CN-116171280-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-05-26 | — | — | CN | claimed |
| WO-2022058920-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-24 | — | — | WO | claimed |
| EP-4214214-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022058920-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-24 | — | — | WO | disclosed |