SCHEMBL29514719

SCHEMBL29514719

O=C(O)c1[nH]nnc1Oc1ccc(-c2ccc(Cl)c(Cl)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22816833 1.00 HAO1 (0.60) HAO1
Trifluoroacetic Acid SCHEMBL22807510 0.93 HAO1 (0.55) HAO1
SCHEMBL29514831 0.89 HAO1 (0.67) HAO1
SCHEMBL22608757 0.89 HAO1 (0.67) HAO1
SCHEMBL22608101 0.87 HAO1 (0.78) HAO1
SCHEMBL29490728 0.84 HAO1 (0.53) HAO1
SCHEMBL22807363 0.84 HAO1 (0.53) HAO1
SCHEMBL22807358 0.84 HAO1 (0.53) HAO1
SCHEMBL22816927 0.83 CYP1A2 (0.45) HAO1
SCHEMBL23319959 0.83 HAO1 (0.62) HAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117126151-A Glycolate oxidase inhibitors for use in the treatment of disease 生物马林药物股份有限公司 2023-11-28 CN disclosed
CN-117069713-A Glycolate oxidase inhibitors for use in the treatment of disease 生物马林药物股份有限公司 2023-11-17 CN disclosed
CN-117069712-A Glycolate oxidase inhibitors for use in the treatment of disease 生物马林药物股份有限公司 2023-11-17 CN disclosed
CN-117024420-A Glycolate oxidase inhibitors for use in the treatment of disease 生物马林药物股份有限公司 2023-11-10 CN disclosed
CN-114258390-A Glycolate oxidase inhibitors for disease treatment 生物马林药物股份有限公司 2022-03-29 CN disclosed