SCHEMBL29514738

SCHEMBL29514738

O=C(O)c1[nH]nnc1OC1CCc2ccccc2C1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 19/20 0.43
HTR2C P28335 1/20 0.39
SLC6A4 P31645 1/20 0.39
HTR2B P41595 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22816396 1.00 HAO1 (0.43) HAO1HTR2CSLC6A4HTR2B
Trifluoroacetic Acid SCHEMBL22608164 0.93 HAO1 (0.39) HAO1
Trifluoroacetic Acid SCHEMBL29490726 0.93 HAO1 (0.39) HAO1
SCHEMBL22807327 0.83 HAO1 (0.38) HAO1
SCHEMBL22807350 0.83 HAO1 (0.38) HAO1
SCHEMBL22807328 0.83 HAO1 (0.38) HAO1
SCHEMBL22608291 0.83 HAO1 (0.39) HAO1
SCHEMBL22608165 0.82 HTR2C (0.34) HTR2CSLC6A4HTR2B
Trifluoroacetic Acid SCHEMBL22608314 0.78 HAO1 (0.35) HAO1
SCHEMBL22816435 0.75 HCAR2 (0.39) HAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117126151-A Glycolate oxidase inhibitors for use in the treatment of disease 生物马林药物股份有限公司 2023-11-28 CN disclosed
CN-117069713-A Glycolate oxidase inhibitors for use in the treatment of disease 生物马林药物股份有限公司 2023-11-17 CN disclosed
CN-117069712-A Glycolate oxidase inhibitors for use in the treatment of disease 生物马林药物股份有限公司 2023-11-17 CN disclosed
CN-117024420-A Glycolate oxidase inhibitors for use in the treatment of disease 生物马林药物股份有限公司 2023-11-10 CN disclosed
CN-114258390-A Glycolate oxidase inhibitors for disease treatment 生物马林药物股份有限公司 2022-03-29 CN disclosed