Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND1 | P24385 | 15/20 | 0.61 |
| ▸ | CDK6 | Q00534 | 11/20 | 0.61 |
| ▸ | CDK4 | P11802 | 11/20 | 0.59 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.51 |
| ▸ | CDK2 | P24941 | 5/20 | 0.51 |
| ▸ | CCND3 | P30281 | 5/20 | 0.51 |
| ▸ | CDK7 | P50613 | 1/20 | 0.51 |
| ▸ | CCNH | P51946 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 4/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25234169 | 1.00 | CCND1 (0.61) | CCND1CDK6CDK4CCNA2CDK2 | |
| SCHEMBL24322070 | 0.90 | CCND1 (0.60) | CCND1CDK6CDK4CCNA2CDK2 | |
| SCHEMBL24322330 | 0.85 | CCND1 (0.83) | CCND1CDK6CDK4 | |
| SCHEMBL29515056 | 0.85 | CCND1 (0.83) | CCND1CDK6CDK4 | |
| SCHEMBL25695259 | 0.77 | CCND1 (0.82) | CCND1CDK6CDK4CCNA2CDK2 | |
| SCHEMBL30541501 | 0.77 | CCND1 (0.74) | CCND1CDK6CDK4 | |
| SCHEMBL24323642 | 0.76 | CCND1 (0.63) | CCND1CDK6CDK4CCNA2CDK2 | |
| SCHEMBL29514916 | 0.76 | CCND1 (1.00) | CCND1CDK6CDK4 | |
| SCHEMBL24322979 | 0.75 | CCND1 (1.00) | CCND1CDK6CDK4CCNA2CDK2 | |
| SCHEMBL24323475 | 0.75 | CCND1 (1.00) | CCND1CDK6CDK4CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214213-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | Prelude Therapeutics, Incorporated (US) | 2023-07-26 | — | — | EP | claimed |
| WO-2022061273-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2022-03-24 | — | — | WO | claimed |
| EP-4214213-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | Prelude Therapeutics, Incorporated (US) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022061273-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2022-03-24 | — | — | WO | disclosed |