Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND1 | P24385 | 15/20 | 1.00 |
| ▸ | CDK6 | Q00534 | 12/20 | 1.00 |
| ▸ | CDK4 | P11802 | 15/20 | 0.75 |
| ▸ | CDK2 | P24941 | 3/20 | 0.57 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.57 |
| ▸ | CDK9 | P50750 | 2/20 | 0.57 |
| ▸ | CCND3 | P30281 | 2/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.57 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.52 |
| ▸ | CCNK | O75909 | 1/20 | 0.52 |
| ▸ | CDK7 | P50613 | 1/20 | 0.52 |
| ▸ | CCNH | P51946 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25237805 | 1.00 | CCND1 (1.00) | CCND1CDK6CDK4CDK2CCNA2 | |
| SCHEMBL29515005 | 0.86 | CCND1 (1.00) | CCND1CDK6CDK4CDK2CCNA2 | |
| SCHEMBL29514918 | 0.84 | CCND1 (0.84) | CCND1CDK6CDK4CDK2CCNA2 | |
| SCHEMBL24322347 | 0.84 | CCND1 (0.84) | CCND1CDK6CDK4CDK2CCNA2 | |
| SCHEMBL30926572 | 0.83 | CDK6 (0.71) | CCND1CDK6CDK4CDK2CCNA2 | |
| SCHEMBL17477154 | 0.83 | CDK6 (0.71) | CCND1CDK6CDK4CDK2CCNA2 | |
| SCHEMBL17477153 | 0.83 | CDK6 (0.71) | CCND1CDK6CDK4CDK2CCNA2 | |
| SCHEMBL17477176 | 0.83 | CDK6 (0.71) | CCND1CDK6CDK4CDK2CCNA2 | |
| SCHEMBL25235418 | 0.83 | CCND1 (0.79) | CCND1CDK6CDK4 | |
| SCHEMBL29515081 | 0.83 | CCND1 (0.79) | CCND1CDK6CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214213-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | Prelude Therapeutics, Incorporated (US) | 2023-07-26 | — | — | EP | claimed |
| WO-2022061273-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2022-03-24 | — | — | WO | claimed |
| EP-4214213-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | Prelude Therapeutics, Incorporated (US) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022061273-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2022-03-24 | — | — | WO | disclosed |