Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND1 | P24385 | 16/20 | 0.80 |
| ▸ | CDK6 | Q00534 | 15/20 | 0.80 |
| ▸ | CDK4 | P11802 | 8/20 | 0.63 |
| ▸ | CDK2 | P24941 | 3/20 | 0.46 |
| ▸ | CSF1R | P07333 | 2/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.46 |
| ▸ | CCNK | O75909 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CCNH | P51946 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | CCND3 | P30281 | 2/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29515094 | 0.96 | CCND1 (0.78) | CCND1CDK6CDK4CDK2CSF1R | |
| SCHEMBL24322142 | 0.96 | CCND1 (0.84) | CCND1CDK6CDK4CDK2CSF1R | |
| SCHEMBL29514940 | 0.96 | CCND1 (0.84) | CCND1CDK6CDK4CDK2CSF1R | |
| SCHEMBL30541022 | 0.90 | CCND1 (0.80) | CCND1CDK6CDK4CDK2CCNA2 | |
| SCHEMBL25235177 | 0.90 | CCND1 (0.80) | CCND1CDK6CDK4CDK2CCNA2 | |
| SCHEMBL24322062 | 0.89 | CDK6 (0.79) | CCND1CDK6CDK4CDK2CCNA2 | |
| SCHEMBL24322177 | 0.89 | CCND1 (1.00) | CCND1CDK6CDK4CDK2CSF1R | |
| SCHEMBL25282784 | 0.89 | CCND1 (0.82) | CCND1CDK6CDK4CDK2CCNA2 | |
| SCHEMBL25278621 | 0.88 | CCND1 (0.76) | CCND1CDK6CDK4 | |
| SCHEMBL24322946 | 0.87 | CCND1 (0.78) | CCND1CDK6CDK4CDK2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214213-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | Prelude Therapeutics, Incorporated (US) | 2023-07-26 | — | — | EP | claimed |
| WO-2022061273-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2022-03-24 | — | — | WO | claimed |
| EP-4214213-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | Prelude Therapeutics, Incorporated (US) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022061273-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2022-03-24 | — | — | WO | disclosed |