Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 15/20 | 0.54 |
| ▸ | PIK3R2 | O00459 | 15/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 15/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 15/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.54 |
| ▸ | PIK3R5 | Q8WYR1 | 15/20 | 0.54 |
| ▸ | PIK3R3 | Q92569 | 15/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29515355 | 0.88 | PIK3CD (0.57) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL13109 | 0.83 | PIK3CD (0.74) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL18082717 | 0.83 | PIK3CD (0.53) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29515387 | 0.83 | PIK3CD (0.74) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29515155 | 0.82 | PIK3CD (0.58) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL24189188 | 0.81 | PIK3CD (0.50) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29515266 | 0.79 | PIK3CD (0.61) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL24188921 | 0.79 | PIK3CD (0.54) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29515240 | 0.78 | PIK3CD (0.62) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29515405 | 0.77 | PIK3CD (0.61) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022022630-A1 | OXA-AZASPIRO DERIVATIVE, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 江苏恒瑞医药股份有限公司 | 2022-02-03 | — | — | WO | disclosed |