Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.60 |
| ▸ | HTR1A | P08908 | 7/20 | 0.60 |
| ▸ | DRD2 | P14416 | 7/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.60 |
| ▸ | HTR7 | P34969 | 5/20 | 0.56 |
| ▸ | HTR6 | P50406 | 5/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8831833 | 0.82 | HTR2A (0.67) | HTR2AHTR1ADRD2ADRA1DADRA1B | |
| SCHEMBL8831311 | 0.80 | HTR2A (0.70) | HTR2AHTR1ADRD2ADRA1DADRA1B | |
| SCHEMBL8831370 | 0.80 | HTR2A (0.66) | HTR2AHTR1ADRD2ADRA1DADRA1B | |
| SCHEMBL25335774 | 0.80 | HTR2A (0.67) | HTR2AHTR1ADRD2ADRA1DADRA1B | |
| SCHEMBL30515499 | 0.80 | HTR2A (0.67) | HTR2AHTR1ADRD2ADRA1DADRA1B | |
| SCHEMBL8419556 | 0.79 | HTR2A (0.67) | HTR2AHTR1ADRD2ADRA1DADRA1B | |
| SCHEMBL8671981 | 0.78 | HTR2A (0.65) | HTR2AHTR1ADRD2ADRA1DADRA1B | |
| SCHEMBL6185115 | 0.78 | HTR2A (0.65) | HTR2AHTR1ADRD2ADRA1DADRA1B | |
| SCHEMBL792909 | 0.78 | HTR2A (0.65) | HTR2AHTR1ADRD2ADRA1DADRA1B | |
| SCHEMBL7771353 | 0.78 | HTR2A (0.65) | HTR2AHTR1ADRD2ADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109467554-B | Indole-heteroaromatic piperazine (pyridine) derivative and application thereof in anti-depression | 上海医药工业研究院 | 2022-05-10 | — | — | CN | claimed |