Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 16/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22658579 | 1.00 | PTK2 (0.41) | PTK2ADKKDM4EPTGDR2ALDH1A1 | |
| SCHEMBL29517219 | 0.81 | PTK2 (0.59) | PTK2 | |
| SCHEMBL22658779 | 0.81 | PTK2 (0.59) | PTK2 | |
| SCHEMBL22658823 | 0.80 | PTK2 (0.34) | PTK2ADKKDM4EPTGDR2ALDH1A1 | |
| SCHEMBL29517167 | 0.80 | PTK2 (0.34) | PTK2ADKKDM4EPTGDR2ALDH1A1 | |
| SCHEMBL29517496 | 0.78 | PTK2 (0.45) | PTK2 | |
| SCHEMBL29517226 | 0.78 | PTK2 (0.45) | PTK2 | |
| SCHEMBL22658562 | 0.77 | PTK2 (0.46) | PTK2 | |
| SCHEMBL29517228 | 0.77 | PTK2 (0.46) | PTK2 | |
| SCHEMBL22658808 | 0.75 | PTK2 (0.62) | PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113811324-B | Small molecule local Focal Adhesion Kinase (FAK) inhibitors | 达纳-法伯癌症研究公司 | 2024-09-24 | — | — | CN | disclosed |
| EP-3965803-A1 | SMALL-MOLECULE FOCAL ADHESION KINASE (FAK) INHIBITORS | Dana-Farber Cancer Institute, Inc. (US) | 2022-03-16 | — | — | EP | disclosed |