Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.59 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.43 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.43 |
| ▸ | BMP1 | P13497 | 3/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29517310 | 1.00 | GNPAT (0.59) | GNPATTASP1FOLH1RIMKLANAALAD2 | |
| SCHEMBL29517694 | 1.00 | GNPAT (0.59) | GNPATTASP1FOLH1RIMKLANAALAD2 | |
| SCHEMBL29517516 | 1.00 | GNPAT (0.59) | GNPATTASP1FOLH1RIMKLANAALAD2 | |
| SCHEMBL29517873 | 0.97 | GNPAT (0.55) | GNPATTASP1FOLH1RIMKLANAALAD2 | |
| SCHEMBL29517656 | 0.97 | GNPAT (0.55) | GNPATTASP1FOLH1RIMKLANAALAD2 | |
| SCHEMBL29517673 | 0.95 | GNPAT (0.59) | GNPATTASP1FOLH1RIMKLANAALAD2 | |
| SCHEMBL29517231 | 0.94 | GNPAT (0.53) | GNPATTASP1SIRT5 | |
| SCHEMBL24616715 | 0.92 | GNPAT (0.49) | GNPATTASP1BMP1SIRT5ECE1 | |
| SCHEMBL22648312 | 0.92 | GNPAT (0.49) | GNPATTASP1BMP1SIRT5ECE1 | |
| SCHEMBL22640897 | 0.92 | GNPAT (0.49) | GNPATTASP1BMP1SIRT5ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966234-A1 | VASCULAR CHOLESTEROL INHIBITORS AND USE THEREOF | Consejo Superior De Investigaciones Científicas (ES) | 2022-03-16 | — | — | EP | disclosed |