Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 7/20 | 0.37 |
| ▸ | CA9 | Q16790 | 6/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FER | P16591 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31605614 | 0.91 | CA4 (0.42) | CA4CA2CA9CA1CA12 | |
| SCHEMBL31605580 | 0.87 | CA4 (0.44) | CA4CA2CA9CA1CA12 | |
| SCHEMBL31605601 | 0.79 | CA1 (0.39) | CA4CA2CA9CA1CA12 | |
| SCHEMBL31605564 | 0.78 | KAT7 (0.41) | CA4KAT6AKAT7KAT6BKAT5 | |
| Hydrochloric Acid SCHEMBL30590348 | 0.75 | CA1 (0.40) | CA4CA2CA9CA1CA12 | |
| SCHEMBL31605619 | 0.75 | CA12 (0.39) | CA4CA2CA9CA1CA12 | |
| SCHEMBL31605565 | 0.73 | KDR (0.38) | CA4CA2CA9CA1CA12 | |
| SCHEMBL31605547 | 0.72 | KDR (0.35) | CA4CA2CA9CA1CA12 | |
| SCHEMBL31605577 | 0.72 | CA4 (0.38) | CA4CA2CA9CA1CA12 | |
| SCHEMBL21609066 | 0.72 | KAT6A (0.52) | KAT6AKAT7KAT6BKAT5KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114364672-B | Benzisoxazole sulfonamide derivatives | 辉瑞大药厂 | 2024-09-06 | — | — | CN | disclosed |
| CN-114364672-A | Benzisoxazole sulfonamide derivatives | 辉瑞大药厂 | 2022-04-15 | — | — | CN | disclosed |