Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.47 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603080 | 0.79 | APP (0.62) | APPPTPN1NR1H4BACE1ALOX5 | |
| Confluentin SCHEMBL29636442 | 0.78 | APP (1.00) | APPPTPN1NR1H4BACE1ALOX5 | |
| Confluentin SCHEMBL31544928 | 0.78 | APP (1.00) | APPPTPN1NR1H4BACE1ALOX5 | |
| Confluentin SCHEMBL31545320 | 0.78 | APP (1.00) | APPPTPN1NR1H4BACE1ALOX5 | |
| Confluentin SCHEMBL31545250 | 0.78 | APP (1.00) | APPPTPN1NR1H4BACE1ALOX5 | |
| SCHEMBL27160317 | 0.78 | APP (0.63) | APPPTPN1NR1H4BACE1ALOX5 | |
| SCHEMBL27160318 | 0.78 | APP (0.63) | APPPTPN1NR1H4BACE1ALOX5 | |
| SCHEMBL27160316 | 0.78 | APP (0.63) | APPPTPN1NR1H4BACE1ALOX5 | |
| SCHEMBL27414830 | 0.78 | APP (0.63) | APPPTPN1NR1H4BACE1ALOX5 | |
| SCHEMBL21710551 | 0.77 | PTPN1 (0.64) | APPPTPN1ALOX5PTGS1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065981-A1 | BIOMARKERS FOR DETECTING COLORECTAL CANCER OR ADENOMA AND METHODS THEREOF | Precogify Pharmaceutical China Co., Ltd. (CN) | 2022-10-05 | — | — | EP | disclosed |
| US-11462305-B2 | Biomarkers for detecting colorectal cancer or adenoma and methods thereof | Precogify Pharmaceutical China Co., Ltd. (CN) | 2022-10-04 | — | — | US | disclosed |
| US-20220108777-A1 | BIOMARKERS FOR DETECTING COLORECTAL CANCER OR ADENOMA AND METHODS THEREOF | Precogify Pharmaceutical China Co., Ltd. (CN) | 2022-04-07 | — | — | US | disclosed |