Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.80 |
| ▸ | FGFR2 | P21802 | 20/20 | 0.80 |
| ▸ | FGFR4 | P22455 | 20/20 | 0.80 |
| ▸ | FGFR3 | P22607 | 20/20 | 0.80 |
| ▸ | VEGFA | P15692 | 3/20 | 0.80 |
| ▸ | FLT1 | P17948 | 3/20 | 0.80 |
| ▸ | KDR | P35968 | 16/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14901132 | 1.00 | FGFR1 (0.80) | FGFR1FGFR2FGFR4FGFR3VEGFA | |
| SCHEMBL20309580 | 0.93 | FGFR1 (0.68) | FGFR1FGFR2FGFR4FGFR3VEGFA | |
| SCHEMBL14901106 | 0.92 | FGFR1 (0.68) | FGFR1FGFR2FGFR4FGFR3VEGFA | |
| SCHEMBL14901432 | 0.92 | FGFR1 (0.68) | FGFR1FGFR2FGFR4FGFR3VEGFA | |
| SCHEMBL14901348 | 0.92 | FGFR3 (0.67) | FGFR1FGFR2FGFR4FGFR3VEGFA | |
| SCHEMBL14901364 | 0.91 | FGFR1 (0.67) | FGFR1FGFR2FGFR4FGFR3VEGFA | |
| SCHEMBL14901341 | 0.91 | FGFR1 (0.67) | FGFR1FGFR2FGFR4FGFR3VEGFA | |
| SCHEMBL14901497 | 0.91 | FGFR3 (0.66) | FGFR1FGFR2FGFR4FGFR3VEGFA | |
| SCHEMBL14901273 | 0.90 | FGFR1 (0.64) | FGFR1FGFR2FGFR4FGFR3VEGFA | |
| SCHEMBL16125204 | 0.90 | FGFR1 (0.65) | FGFR1FGFR2FGFR4FGFR3VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108632-B | Deuterated triazolopyridazines as kinase modulators | 詹森药业股份有限公司 | 2022-04-19 | — | — | CN | disclosed |