Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 12/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.59 |
| ▸ | RPTOR | Q8N122 | 6/20 | 0.42 |
| ▸ | MLST8 | Q9BVC4 | 6/20 | 0.42 |
| ▸ | PRKDC | P78527 | 2/20 | 0.41 |
| ▸ | RICTOR | Q6R327 | 2/20 | 0.40 |
| ▸ | MAPKAP1 | Q9BPZ7 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL152295 | 1.00 | MTOR (0.59) | MTORPIK3CARPTORMLST8PRKDC | |
| SCHEMBL151621 | 0.83 | MTOR (0.57) | MTORPIK3CARPTORMLST8PRKDC | |
| SCHEMBL29522623 | 0.81 | MTOR (0.62) | MTORPIK3CARPTORMLST8PRKDC | |
| SCHEMBL151708 | 0.81 | MTOR (0.62) | MTORPIK3CARPTORMLST8PRKDC | |
| SCHEMBL154183 | 0.81 | MTOR (0.60) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL29522610 | 0.81 | MTOR (0.60) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL154634 | 0.79 | MTOR (0.63) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL29522003 | 0.79 | MTOR (0.63) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL136021 | 0.75 | MTOR (1.00) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL29523011 | 0.75 | MTOR (1.00) | MTORPIK3CARPTORMLST8RICTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117213-B | Heteroaryl compounds and methods for their synthesis and purification | 西格诺药品有限公司 | 2022-03-18 | — | — | CN | disclosed |