Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 1.00 |
| ▸ | PIK3CA | P42336 | 13/20 | 1.00 |
| ▸ | RPTOR | Q8N122 | 10/20 | 1.00 |
| ▸ | MLST8 | Q9BVC4 | 10/20 | 1.00 |
| ▸ | RICTOR | Q6R327 | 3/20 | 0.78 |
| ▸ | MAPKAP1 | Q9BPZ7 | 3/20 | 0.78 |
| ▸ | CSF1R | P07333 | 2/20 | 0.78 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.59 |
| ▸ | FLT4 | P35916 | 1/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.59 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155597 | 1.00 | MTOR (1.00) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL29522200 | 1.00 | MTOR (1.00) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL154223 | 1.00 | MTOR (1.00) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL154224 | 1.00 | MTOR (1.00) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL150651 | 0.95 | MTOR (0.90) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL154939 | 0.95 | MTOR (0.90) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL155536 | 0.95 | MTOR (0.90) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL135899 | 0.95 | MTOR (0.90) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL29522040 | 0.95 | MTOR (0.90) | MTORPIK3CARPTORMLST8RICTOR | |
| SCHEMBL29521998 | 0.95 | MTOR (0.90) | MTORPIK3CARPTORMLST8RICTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117213-B | Heteroaryl compounds and methods for their synthesis and purification | 西格诺药品有限公司 | 2022-03-18 | — | — | CN | disclosed |