Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.67 |
| ▸ | FGFR2 | P21802 | 6/20 | 0.58 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.58 |
| ▸ | FGFR3 | P22607 | 6/20 | 0.58 |
| ▸ | EGFR | P00533 | 5/20 | 0.58 |
| ▸ | SRC | P12931 | 4/20 | 0.58 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.58 |
| ▸ | PRKCG | P05129 | 2/20 | 0.58 |
| ▸ | PRKCB | P05771 | 2/20 | 0.58 |
| ▸ | PRKCA | P17252 | 2/20 | 0.58 |
| ▸ | PRKCH | P24723 | 2/20 | 0.58 |
| ▸ | PRKCI | P41743 | 2/20 | 0.58 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.58 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.58 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.58 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.58 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL928330 | 0.92 | FGFR1 (0.67) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL928985 | 0.88 | FGFR1 (0.74) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL8122737 | 0.81 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL927322 | 0.78 | FGFR1 (0.57) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL8127381 | 0.74 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL8122237 | 0.73 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL12908056 | 0.73 | FGFR1 (0.55) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL12943335 | 0.72 | FGFR1 (0.52) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL928109 | 0.72 | FGFR1 (0.68) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL927776 | 0.72 | FGFR1 (0.53) | FGFR1FGFR2FGFR4FGFR3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099797-B1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2010-09-29 | — | — | EP | disclosed |