Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 17/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.67 |
| ▸ | RPTOR | Q8N122 | 8/20 | 0.67 |
| ▸ | MLST8 | Q9BVC4 | 8/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29543605 | 0.89 | MTOR (0.64) | MTORPIK3CARPTORMLST8KCNH2 | |
| SCHEMBL137345 | 0.89 | MTOR (0.64) | MTORPIK3CARPTORMLST8KCNH2 | |
| SCHEMBL138483 | 0.87 | MTOR (0.64) | MTORPIK3CARPTORMLST8KCNH2 | |
| SCHEMBL138845 | 0.84 | MTOR (0.68) | MTORPIK3CARPTORMLST8KCNH2 | |
| SCHEMBL29522192 | 0.84 | MTOR (0.68) | MTORPIK3CARPTORMLST8KCNH2 | |
| SCHEMBL29522226 | 0.82 | MTOR (0.56) | MTORPIK3CARPTORMLST8KCNH2 | |
| SCHEMBL138560 | 0.82 | MTOR (0.88) | MTORPIK3CARPTORMLST8 | |
| SCHEMBL29522104 | 0.82 | MTOR (0.88) | MTORPIK3CARPTORMLST8 | |
| SCHEMBL29522326 | 0.81 | MTOR (0.80) | MTORPIK3CARPTORMLST8KCNH2 | |
| SCHEMBL29522028 | 0.80 | MTOR (1.00) | MTORPIK3CARPTORMLST8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117213-B | Heteroaryl compounds and methods for their synthesis and purification | 西格诺药品有限公司 | 2022-03-18 | — | — | CN | disclosed |