SCHEMBL29523213

SCHEMBL29523213

Ic1csc2cnc(Nc3cccc(N4CCOCC4)c3)nc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2 Q05397 4/20 0.56
CCNT1 O60563 5/20 0.55
CDK2 P24941 5/20 0.55
CDK9 P50750 5/20 0.55
CCNE1 P24864 1/20 0.55
HDAC3 O15379 1/20 0.53
HDAC1 Q13547 1/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
CCNA2 P20248 4/20 0.51
PLK4 O00444 1/20 0.50
CDK1 P06493 1/20 0.49
CCNB1 P14635 1/20 0.49
CDK7 P50613 1/20 0.49
CCNH P51946 1/20 0.49
CCNA1 P78396 1/20 0.49
RIPK2 O43353 2/20 0.49
NTRK1 P04629 1/20 0.49
PKMYT1 Q99640 1/20 0.47
CAMK2D Q13557 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1674188 1.00 PTK2 (0.56) PTK2CCNT1CDK2CDK9CCNE1
SCHEMBL1674318 0.88 PTK2 (0.58) PTK2CCNT1CDK2CDK9CCNE1
SCHEMBL29523487 0.88 PTK2 (0.58) PTK2CCNT1CDK2CDK9CCNE1
SCHEMBL29523174 0.79 SYK (0.52) PTK2CDK2
SCHEMBL1674326 0.79 SYK (0.52) PTK2CDK2
SCHEMBL17461676 0.77 PTK2 (0.78) PTK2JAK2JAK1JAK3
SCHEMBL29523766 0.77 PTK2 (0.66) PTK2JAK2JAK1JAK3
SCHEMBL1674325 0.77 PTK2 (0.66) PTK2JAK2JAK1JAK3
SCHEMBL1674051 0.76 AURKA (0.50) PTK2PLK4CDK1JAK2JAK3
SCHEMBL29523208 0.76 AURKA (0.50) PTK2PLK4CDK1JAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735463-A1 COMPOUNDS AND USES THEREFOR GLYCOSYNNOVATIONS PTY LTD (AU) 2026-05-06 EP disclosed
EP-4735462-A1 COMPOUNDS AND USES THEREFOR GLYCOSYNNOVATIONS PTY LTD (AU) 2026-05-06 EP disclosed
EP-4565577-A1 INHIBITORS AND USES THEREFOR Macquarie University (AU) 2025-06-11 EP disclosed
WO-2025000061-A1 COMPOUNDS AND USES THEREFOR Glycosynnovations Pty Ltd (AU) 2025-01-02 WO disclosed
WO-2025000059-A1 COMPOUNDS AND USES THEREFOR Glycosynnovations Pty Ltd (AU) 2025-01-02 WO disclosed
CN-117881403-A Thionucleosides as antiviral agents 爱莫里大学 2024-04-12 CN disclosed
CN-117858711-A Nucleoside and nucleotide analogs as antiviral agents 爱莫里大学 2024-04-09 CN disclosed
CN-117769427-A Modified nucleosides and nucleotide analogues as antiviral agents for coronaviruses and other viruses 埃默里大学 2024-03-26 CN disclosed
EP-4319762-A2 NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS Emory University (US) 2024-02-14 EP disclosed
EP-4319763-A2 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES Emory University (US) 2024-02-14 EP disclosed
EP-4319764-A2 THIONUCLEOSIDES AS ANTIVIRAL AGENTS Emory University (US) 2024-02-14 EP disclosed
WO-2024026540-A1 INHIBITORS AND USES THEREFOR MACQUARIE UNIVERSITY (AU) 2024-02-08 WO disclosed
WO-2022217155-A2 THIONUCLEOSIDES AS ANTIVIRAL AGENTS EMORY UNIVERSITY (US) 2022-10-13 WO disclosed
WO-2022217154-A2 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES EMORY UNIVERSITY (US) 2022-10-13 WO disclosed
WO-2022217153-A2 NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS EMORY UNIVERSITY (US) 2022-10-13 WO disclosed
WO-2022170396-A1 AGENTS AND METHODS FOR THERAPY AND PROPHYLAXIS ViraLok Therapeutics Pty Ltd (AU) 2022-08-18 WO disclosed
EP-3980400-A1 PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS Emory University (US) 2022-04-13 EP disclosed