SCHEMBL29523219

SCHEMBL29523219

CN(C)S(=O)(=O)c1cccc(-c2csc3cnc(Nc4ccc(N5CCOCC5)cc4)nc23)c1

nearest known ligand 0.74

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTK2 Q05397 18/20 0.74
JAK2 O60674 2/20 0.60
BRD4 O60885 2/20 0.60
LCK P06239 1/20 0.60
FYN P06241 1/20 0.60
FES P07332 1/20 0.60
RET P07949 1/20 0.60
ROS1 P08922 1/20 0.60
CDK4 P11802 1/20 0.60
SRC P12931 1/20 0.60
JAK1 P23458 1/20 0.60
TYK2 P29597 1/20 0.60
JAK3 P52333 1/20 0.60
EPHB1 P54762 1/20 0.60
CSNK2A1 P68400 1/20 0.60
DDR1 Q08345 1/20 0.60
KCNH2 Q12809 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1674005 1.00 PTK2 (0.74) PTK2JAK2BRD4LCKFYN
SCHEMBL30540747 0.89 PTK2 (0.75) PTK2JAK2BRD4LCKFYN
SCHEMBL29523727 0.88 PTK2 (0.73) PTK2JAK2BRD4LCKFYN
SCHEMBL1674397 0.88 PTK2 (0.73) PTK2JAK2BRD4LCKFYN
SCHEMBL1674050 0.85 PTK2 (1.00) PTK2JAK2BRD4LCKFYN
SCHEMBL18334677 0.84 PTK2 (0.74) PTK2JAK2BRD4LCKFYN
SCHEMBL29523722 0.84 PTK2 (0.74) PTK2JAK2BRD4LCKFYN
SCHEMBL1674187 0.84 PTK2 (0.74) PTK2JAK2BRD4LCKFYN
SCHEMBL17461676 0.83 PTK2 (0.78) PTK2JAK2BRD4LCKFYN
SCHEMBL1673993 0.83 PTK2 (0.78) PTK2JAK2BRD4LCKFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735462-A1 COMPOUNDS AND USES THEREFOR GLYCOSYNNOVATIONS PTY LTD (AU) 2026-05-06 EP disclosed
EP-4735463-A1 COMPOUNDS AND USES THEREFOR GLYCOSYNNOVATIONS PTY LTD (AU) 2026-05-06 EP disclosed
EP-4565577-A1 INHIBITORS AND USES THEREFOR Macquarie University (AU) 2025-06-11 EP disclosed
EP-4556010-A2 JAK INHIBITORS FOR USE IN THE PREVENTION OR TREATMENT OF A VIRAL DISEASE CAUSED BY A CORONAVIRIDAE Emory University (US) 2025-05-21 EP disclosed
WO-2025000061-A1 COMPOUNDS AND USES THEREFOR Glycosynnovations Pty Ltd (AU) 2025-01-02 WO disclosed
WO-2025000059-A1 COMPOUNDS AND USES THEREFOR Glycosynnovations Pty Ltd (AU) 2025-01-02 WO disclosed
EP-4319764-A2 THIONUCLEOSIDES AS ANTIVIRAL AGENTS Emory University (US) 2024-02-14 EP disclosed
EP-4319762-A2 NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS Emory University (US) 2024-02-14 EP disclosed
EP-4319763-A2 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES Emory University (US) 2024-02-14 EP disclosed
WO-2024026540-A1 INHIBITORS AND USES THEREFOR MACQUARIE UNIVERSITY (AU) 2024-02-08 WO disclosed
WO-2022217155-A2 THIONUCLEOSIDES AS ANTIVIRAL AGENTS EMORY UNIVERSITY (US) 2022-10-13 WO disclosed
WO-2022217154-A2 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES EMORY UNIVERSITY (US) 2022-10-13 WO disclosed
WO-2022217153-A2 NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS EMORY UNIVERSITY (US) 2022-10-13 WO disclosed
WO-2022170396-A1 AGENTS AND METHODS FOR THERAPY AND PROPHYLAXIS ViraLok Therapeutics Pty Ltd (AU) 2022-08-18 WO disclosed
EP-3980400-A1 PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS Emory University (US) 2022-04-13 EP disclosed