SCHEMBL29523374

SCHEMBL29523374

Nc1ccc(-c2csc3cnc(Nc4ccc(N5CCOCC5)cc4)nc23)cc1

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTK2 Q05397 17/20 0.65
PLK4 O00444 1/20 0.53
SYK P43405 1/20 0.52
LCK P06239 1/20 0.51
FYN P06241 1/20 0.51
FES P07332 1/20 0.51
RET P07949 1/20 0.51
ROS1 P08922 1/20 0.51
CDK4 P11802 1/20 0.51
SRC P12931 1/20 0.51
JAK1 P23458 1/20 0.51
TYK2 P29597 1/20 0.51
JAK3 P52333 1/20 0.51
EPHB1 P54762 1/20 0.51
CSNK2A1 P68400 1/20 0.51
DDR1 Q08345 1/20 0.51
KCNH2 Q12809 1/20 0.51
JAK2 O60674 1/20 0.51
BRD4 O60885 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1674303 1.00 PTK2 (0.65) PTK2PLK4SYKLCKFYN
SCHEMBL18334676 0.90 PTK2 (0.65) PTK2LCKFYNFESRET
SCHEMBL1674187 0.89 PTK2 (0.74) PTK2PLK4LCKFYNFES
SCHEMBL29523722 0.89 PTK2 (0.74) PTK2PLK4LCKFYNFES
SCHEMBL1674323 0.89 PTK2 (0.66) PTK2LCKFYNFESRET
SCHEMBL1674378 0.88 PTK2 (0.63) PTK2LCKFYNFESRET
SCHEMBL14853047 0.87 PTK2 (0.67) PTK2LCKFYNFESRET
SCHEMBL1674156 0.87 PTK2 (0.82) PTK2LCKFYNFESRET
SCHEMBL1674042 0.87 PTK2 (0.61) PTK2PLK4LCKFYNFES
SCHEMBL29523019 0.87 PTK2 (0.61) PTK2PLK4LCKFYNFES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735463-A1 COMPOUNDS AND USES THEREFOR GLYCOSYNNOVATIONS PTY LTD (AU) 2026-05-06 EP disclosed
EP-4735462-A1 COMPOUNDS AND USES THEREFOR GLYCOSYNNOVATIONS PTY LTD (AU) 2026-05-06 EP disclosed
EP-4565577-A1 INHIBITORS AND USES THEREFOR Macquarie University (AU) 2025-06-11 EP disclosed
WO-2025000059-A1 COMPOUNDS AND USES THEREFOR Glycosynnovations Pty Ltd (AU) 2025-01-02 WO disclosed
WO-2025000061-A1 COMPOUNDS AND USES THEREFOR Glycosynnovations Pty Ltd (AU) 2025-01-02 WO disclosed
CN-117881403-A Thionucleosides as antiviral agents 爱莫里大学 2024-04-12 CN disclosed
CN-117858711-A Nucleoside and nucleotide analogs as antiviral agents 爱莫里大学 2024-04-09 CN disclosed
CN-117769427-A Modified nucleosides and nucleotide analogues as antiviral agents for coronaviruses and other viruses 埃默里大学 2024-03-26 CN disclosed
WO-2024026540-A1 INHIBITORS AND USES THEREFOR MACQUARIE UNIVERSITY (AU) 2024-02-08 WO disclosed
WO-2022170396-A1 AGENTS AND METHODS FOR THERAPY AND PROPHYLAXIS ViraLok Therapeutics Pty Ltd (AU) 2022-08-18 WO disclosed